Developmental Research (DR)/Pilot and Feasibility (P&F) Program The primary goals of the Developmental Research / Pilot and Feasibility Program are: 1. To provide funding to eligible applicants for novel projects focused on Urologic research. 2. To provide mentorship for new and established investigators. Mentors chosen from the Center faculty will guide both career and project development for new investigators, and will guide the development of new studies in Urologic research for established investigators. Investigators who apply for funding through this mechanism must be new investigators without current or past NIH support as a principal investigator; or established investigators without current or past NIH support in the proposed area of Urologic research or who wish to pursue other areas of Urologic research for which they do not have current or past NIH support. Projects eligible for funding through this mechanism may include (but are not limited to) those that focus on genitourinary development, Urologic disease or disorders, explore new basic areas that may have clinical research application, or provide new and innovative approaches to the study urological disease. Multidisciplinary projects are encouraged. All Developmental studies are expected to lead to competitive investigator-initiated RO1 research grant applications. Applications will be considered through a rigorous pre-proposal and full proposal process. Successful applicants will be provided with evaluation and assistance by the Center Steering Committee. The Program will be directed by Jill A. Macoska, PhD and Stuart Wolf, kiD. The inclusion of both a basic scientist (Dr. Macoska) and a clinical scientist (Dr. Wolf) should ensure that both pre-clinical and clinical expertise will be available to the Program.